Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17760974 | 0.87 | FFAR1 (0.47) | FFAR1NPSR1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL22630848 | 0.87 | FFAR1 (0.47) | FFAR1NPSR1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL9513688 | 0.82 | FFAR1 (0.56) | FFAR1NPSR1TAS1R3TAS1R1LMNA | |
| SCHEMBL15641272 | 0.80 | AKR1C3 (0.63) | TAS1R3TAS1R1ALDH1A1TSHRLMNA | |
| SCHEMBL15641270 | 0.80 | AKR1C3 (0.63) | TAS1R3TAS1R1ALDH1A1TSHRLMNA | |
| SCHEMBL7786568 | 0.79 | WDR5 (0.46) | FFAR1NPSR1POLBMAPTGAA | |
| SCHEMBL13052228 | 0.79 | ALDH1A1 (0.48) | TAS1R3TAS1R1ALDH1A1LMNAMEN1 | |
| SCHEMBL14905538 | 0.78 | TAS1R3 (0.46) | FFAR1NPSR1TAS1R3TAS1R1ALDH1A1 | |
| Bromide SCHEMBL9765241 | 0.76 | CSNK2A1 (0.41) | TAS1R3TAS1R1ALDH1A1MEN1KMT2A | |
| SCHEMBL7626560 | 0.76 | LMNA (0.49) | NPSR1TAS1R3TAS1R1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |