Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100322 | 0.95 | HPGD (0.44) | CHEK1POLBHPGDNPC1RAB9A | |
| SCHEMBL99117 | 0.92 | CHEK1 (0.38) | CHEK1POLBHPGDNPC1RAB9A | |
| SCHEMBL99659 | 0.91 | POLB (0.40) | POLBHPGDNPC1RAB9ATRPV1 | |
| SCHEMBL15823470 | 0.89 | ALDH1A1 (0.37) | POLBNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL99375 | 0.88 | NPC1 (0.49) | POLBHPGDNPC1RAB9ATRPV1 | |
| SCHEMBL102617 | 0.87 | HCAR2 (0.39) | POLBHPGDNPC1RAB9ATRPV1 | |
| SCHEMBL132259 | 0.87 | CHRM3 (0.45) | CHEK1 | |
| SCHEMBL101634 | 0.87 | POLB (0.46) | CHEK1POLBHPGDNPC1RAB9A | |
| SCHEMBL99141 | 0.87 | NPC1 (0.48) | POLBHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL98939 | 0.86 | CHRM3 (0.43) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |