Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765299 | 0.83 | SMN1; SMN2 (0.51) | ALDH1A1MAPTHTTPOLBNPSR1 | |
| SCHEMBL9765306 | 0.80 | KCNA5 (0.55) | ALDH1A1TDP1HTTPOLBSMN1; SMN2 | |
| SCHEMBL9765264 | 0.80 | KCNA5 (0.55) | ALDH1A1TDP1HTTPOLBSMN1; SMN2 | |
| SCHEMBL9765315 | 0.75 | HTT (0.49) | ALDH1A1TDP1HTTTAS1R3TAS1R1 | |
| SCHEMBL9514108 | 0.75 | FFAR1 (0.50) | ALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL9765262 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL9963706 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTTAS1R3TAS1R1 | |
| SCHEMBL11103819 | 0.72 | L3MBTL1 (0.53) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1138883 | 0.72 | MEN1 (0.50) | ALDH1A1MAPTHTTPOLBKDM4E | |
| SCHEMBL21165788 | 0.71 | SLC6A2 (0.49) | MAPTTDP1TAS1R3TAS1R1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |