Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915242 | 0.88 | ALDH1A1 (0.46) | HPGDLMNAPOLBCYP2C19EPHX1 | |
| SCHEMBL2915594 | 0.88 | ALDH1A1 (0.46) | HPGDLMNAPOLBCYP2C19EPHX1 | |
| SCHEMBL5918571 | 0.88 | GABBR2 (0.50) | LMNAPOLBCYP2C19EPHX1HSD17B10 | |
| SCHEMBL20342100 | 0.88 | GABBR2 (0.50) | LMNAPOLBCYP2C19EPHX1HSD17B10 | |
| SCHEMBL1977280 | 0.88 | ALDH1A1 (0.46) | HPGDLMNAPOLBCYP2C19EPHX1 | |
| SCHEMBL25575127 | 0.88 | GABBR2 (0.50) | LMNAPOLBCYP2C19EPHX1HSD17B10 | |
| SCHEMBL10888710 | 0.84 | LMNA (0.47) | HPGDLMNAPOLBCYP2C19EPHX1 | |
| SCHEMBL13544797 | 0.84 | EPHX1 (0.50) | LMNAPOLBCYP2C19EPHX1SMN1; SMN2 | |
| SCHEMBL435642 | 0.82 | L3MBTL1 (0.63) | HPGDLMNAPOLBCYP2C19SMN1; SMN2 | |
| SCHEMBL11918239 | 0.82 | CYP2C19 (0.41) | LMNACYP2C19EPHX1HSD17B10ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006567-A | Polycarbonates with high impact strength | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | claimed |
| US-5006567-A | Polycarbonates with high impact strength | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | disclosed |
| US-5006567-A | Polycarbonates with high impact strength | THE DOW CHEMICAL COMPANY (US) | 1991-04-09 | — | — | US | disclosed |