Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.54 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034087 | 0.85 | ALDH1A1 (0.50) | TBXAS1PLOD2GAAALDH1A1APP | |
| SCHEMBL9164487 | 0.82 | PLOD2 (0.49) | TBXAS1PLOD2GAAALDH1A1APP | |
| SCHEMBL9356364 | 0.82 | CYP2C19 (0.55) | TBXAS1ALDH1A1MMP1MMP2MMP3 | |
| SCHEMBL5162022 | 0.80 | ALDH1A1 (0.55) | TBXAS1PLOD2GAAALDH1A1APP | |
| SCHEMBL24434284 | 0.79 | EPHX2 (0.46) | TBXAS1PLOD2GAAALDH1A1APP | |
| SCHEMBL31249622 | 0.77 | MAPT (0.45) | TBXAS1PLOD2GAAALDH1A1APP | |
| SCHEMBL6900351 | 0.77 | ALDH1A1 (0.51) | TBXAS1PLOD2GAAALDH1A1APP | |
| SCHEMBL6511843 | 0.77 | MDM2 (0.62) | TBXAS1PLOD2GAAALDH1A1APP | |
| SCHEMBL10975235 | 0.77 | MDM2 (0.55) | ALDH1A1MMP1MMP2MMP3MMP7 | |
| SCHEMBL27623816 | 0.77 | TBXAS1 (0.57) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |