Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343938 | 0.83 | TDP1 (0.45) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL10702510 | 0.81 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL9765875 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TDP1HPGDKDM4EPOLB | |
| SCHEMBL9765814 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TDP1POLBMAPTGAA | |
| SCHEMBL9343857 | 0.79 | TDP1 (0.41) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL9723051 | 0.79 | POLB (0.42) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL9343914 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL9339580 | 0.78 | TDP1 (0.47) | ALDH1A1TDP1CYP3A4HPGDALOX15 | |
| SCHEMBL9765847 | 0.76 | GAA (0.39) | ALDH1A1TDP1KDM4EMAPTGAA | |
| SCHEMBL23001566 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990512-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0357201-A2 | Pyridyl pyrimidinone derivatives with an insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-07 | — | — | EP | disclosed |