Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765814 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTNPSR1POLBTDP1 | |
| SCHEMBL9341586 | 0.81 | KDM5B (0.37) | ALDH1A1KDM5B | |
| SCHEMBL9765847 | 0.80 | GAA (0.39) | ALDH1A1KDM5BMAPTNPSR1TDP1 | |
| SCHEMBL9765906 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTPOLBTDP1KDM4E | |
| SCHEMBL10701521 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTNPSR1POLBKDM4E | |
| SCHEMBL9723095 | 0.77 | HCAR1 (0.36) | ALDH1A1KDM5BPOLB | |
| SCHEMBL9731349 | 0.77 | KDM5B (0.34) | ALDH1A1KDM5B | |
| SCHEMBL9339481 | 0.76 | GABRA2 (0.36) | ALDH1A1KDM5BNPSR1 | |
| SCHEMBL9765862 | 0.74 | KDM4E (0.44) | ALDH1A1MAPTTDP1KDM4EGAA | |
| SCHEMBL9582173 | 0.73 | DDR1 (0.32) | KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990512-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0357201-A2 | Pyridyl pyrimidinone derivatives with an insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-07 | — | — | EP | disclosed |