Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766044 | 0.83 | SIGMAR1 (0.54) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| SCHEMBL9765990 | 0.82 | SIGMAR1 (0.54) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| SCHEMBL9400880 | 0.72 | HTT (0.55) | KDM4EGAA | |
| SCHEMBL23251897 | 0.71 | OGA (0.47) | SIGMAR1DRD2HTR1A | |
| SCHEMBL25678432 | 0.71 | OGA (0.47) | SIGMAR1DRD2HTR1A | |
| SCHEMBL7246517 | 0.71 | DRD2 (0.82) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| Hydrochloric Acid SCHEMBL21528219 | 0.70 | OGA (0.46) | SIGMAR1DRD2HTR1A | |
| SCHEMBL9532652 | 0.70 | DRD2 (0.56) | SIGMAR1KDM4EDRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9766015 | 0.70 | DRD2 (0.80) | SIGMAR1KDM4ECYP1A2GAACYP2C9 | |
| SCHEMBL9765986 | 0.69 | SIGMAR1 (0.61) | SIGMAR1KDM4ECYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994460-A | Treatment or prevention of disorders resulting from central nervous system anoxia | BRISTOL-MYERS SQUIBB CO. (US) | 1991-02-19 | — | — | US | disclosed |