Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364439 | 0.84 | ALDH1A1 (0.49) | KDM4EHSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL8367148 | 0.84 | AKR1C3 (0.49) | KDM4EHSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL8457832 | 0.84 | KDM4E (0.48) | MEN1KMT2ALMNAPOLBKDM4E | |
| SCHEMBL9157244 | 0.82 | KDM4E (0.56) | KDM4EHSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL8366206 | 0.82 | KDM4E (0.55) | LMNAKDM4EHSD17B10MAPTHPGD | |
| SCHEMBL9156302 | 0.82 | KDM4E (0.46) | MEN1KMT2ALMNAKDM4EHSD17B10 | |
| SCHEMBL8366369 | 0.81 | ALDH1A1 (0.44) | KDM4EHSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL11888513 | 0.79 | CDK2 (0.47) | MEN1KMT2ALMNAPOLBKDM4E | |
| SCHEMBL1775541 | 0.75 | ATM (0.46) | KDM4EHSD17B10MAPTHPGDALDH1A1 | |
| SCHEMBL2266978 | 0.74 | KDM4E (0.51) | MEN1KMT2ALMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983607-A | ANTISEROTONINERGIC ACTIVITY | SYNTHELABO (FR) | 1991-01-08 | — | — | US | disclosed |