Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | BRD1 | O95696 | 5/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 2/20 | 0.38 |
| ▸ | BRPF3 | Q9ULD4 | 3/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367875 | 0.86 | BRD4 (0.45) | ALDH1A1MAPTKDM4EHPGDBRD1 | |
| SCHEMBL8366314 | 0.83 | BRD1 (0.42) | MAPTHSD17B10BRD1BRPF1EGFR | |
| SCHEMBL9766045 | 0.81 | MEN1 (0.51) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8366274 | 0.80 | BRD1 (0.42) | MAPTKDM4EBRD1BRPF1EGFR | |
| SCHEMBL8457832 | 0.80 | KDM4E (0.48) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8364439 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8367148 | 0.80 | AKR1C3 (0.49) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL23609754 | 0.77 | KDM4E (0.47) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL9157244 | 0.77 | KDM4E (0.56) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL8366206 | 0.77 | KDM4E (0.55) | ALDH1A1MAPTKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850235-B1 | QUINOLEIN-2(1H)-ONE DERIVATIVES AS SEROTONIN ANTAGONISTS | SANOFI SYNTHELABO (FR) | 1999-12-01 | — | — | EP | disclosed |
| US-5958924-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS, RESTENOSIS, ANTICOALUGANTS, RESPIRATORY SYSTEM DISORDERS | SYNTHELABO (FR) | 1999-09-28 | — | — | US | disclosed |