Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 1.00 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9765999 | 0.99 | SIGMAR1 (0.98) | SIGMAR1HTR1ADRD2DRD1DRD5 | |
| SCHEMBL9766069 | 0.80 | SIGMAR1 (0.67) | SIGMAR1HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL9766006 | 0.79 | SIGMAR1 (1.00) | SIGMAR1HTR1ADRD2KDM4ECYP1A2 | |
| SCHEMBL9766055 | 0.78 | SIGMAR1 (0.64) | SIGMAR1HTR1ADRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9766032 | 0.78 | SIGMAR1 (0.98) | SIGMAR1HTR1ADRD2KDM4ECYP1A2 | |
| SCHEMBL9765984 | 0.76 | SIGMAR1 (1.00) | SIGMAR1HTR1ADRD2DRD1DRD5 | |
| SCHEMBL7521159 | 0.76 | SIGMAR1 (0.66) | SIGMAR1HTR1ADRD2KDM4ECYP1A2 | |
| SCHEMBL9766002 | 0.74 | SIGMAR1 (0.58) | SIGMAR1HTR1ADRD2HTR2AKDM4E | |
| SCHEMBL30350966 | 0.73 | SIGMAR1 (0.66) | SIGMAR1HTR1ADRD2KDM4ECYP1A2 | |
| SCHEMBL9401039 | 0.72 | HTR1A (1.00) | SIGMAR1HTR1ADRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994460-A | Treatment or prevention of disorders resulting from central nervous system anoxia | BRISTOL-MYERS SQUIBB CO. (US) | 1991-02-19 | — | — | US | claimed |
| EP-0400661-A1 | Agents for treatment of brain ischemia | Bristol-Myers Squibb Company (US) | 1990-12-05 | — | — | EP | claimed |