Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737418 | 0.66 | CA2 (0.37) | NFE2L2POLB | |
| Bromide SCHEMBL9766193 | 0.65 | CDC25A (0.37) | POLB | |
| Bromide SCHEMBL9766218 | 0.65 | ALDH2 (0.46) | POLB | |
| SCHEMBL15171477 | 0.62 | NFE2L2 (0.45) | NFE2L2 | |
| Bromide SCHEMBL986439 | 0.61 | ALDH1A1 (0.49) | POLB | |
| SCHEMBL691387 | 0.61 | — | — | |
| SCHEMBL20101941 | 0.60 | NFE2L2 (0.40) | NFE2L2 | |
| SCHEMBL3485633 | 0.59 | — | — | |
| SCHEMBL7548600 | 0.59 | — | — | |
| SCHEMBL14731971 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064649-A | CEPHALOSPORIN DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0359536-A2 | Cephalosporin compounds, process for their preparation and pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1990-03-21 | — | — | EP | disclosed |