Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193280 | 0.82 | ALDH1A1 (0.41) | ALDH1A1SIRT1RAB9ALMNAMAPT | |
| SCHEMBL11199670 | 0.78 | HTR7 (0.40) | ALDH1A1TP53MAPK1KDM4EMEN1 | |
| SCHEMBL9768371 | 0.75 | RAB9A (0.43) | CA2ALDH1A1MAOBSIRT1RAB9A | |
| SCHEMBL3485633 | 0.69 | — | — | |
| SCHEMBL12713998 | 0.67 | NFE2L2 (0.37) | NFE2L2 | |
| SCHEMBL27282059 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL15171477 | 0.67 | NFE2L2 (0.45) | SLC6A3NFE2L2GAA | |
| SCHEMBL15818217 | 0.66 | NFE2L2 (0.34) | NFE2L2 | |
| SCHEMBL21306498 | 0.66 | MEN1 (0.45) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| Bromide SCHEMBL9766103 | 0.66 | NFE2L2 (0.34) | POLBNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417377-B1 | Process for preparing enantiomer-enriched amino- and hydroxyfuranones | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2002-07-09 | — | — | US | disclosed |
| US-4374249-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-02-15 | — | — | US | disclosed |