Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679666 | 0.82 | LMNA (0.44) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL19900445 | 0.74 | POLB (0.40) | ALDH1A1KMT2APOLBHPGDMAPT | |
| SCHEMBL1326560 | 0.69 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2APOLBGPBAR1 | |
| SCHEMBL11911198 | 0.68 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL11368118 | 0.68 | LMNA (0.57) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL19802451 | 0.67 | HSP90AA1 (0.46) | LMNAKMT2AMEN1POLBMAPT | |
| SCHEMBL11893412 | 0.66 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL14363623 | 0.66 | L3MBTL1 (0.50) | ALDH1A1SMN1; SMN2LMNAKMT2AGPBAR1 | |
| SCHEMBL1179711 | 0.66 | NR1H4 (0.38) | ALDH1A1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL10774901 | 0.66 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064649-A | CEPHALOSPORIN DERIVATIVES | BEECHAM GROUP P.L.C. (GB) | 1991-11-12 | — | — | US | claimed |