SCHEMBL9766384

SCHEMBL9766384

O=C(O)c1cccc2ccc(C3CCCCC3)cc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 2/20 0.57
KMO O15229 1/20 0.55
DHODH Q02127 1/20 0.51
NR4A1 P22736 1/20 0.49
NR4A2 P43354 1/20 0.49
NR4A3 Q92570 1/20 0.49
TBK1 Q9UHD2 5/20 0.47
IKBKE Q14164 2/20 0.46
SERPINE1 P05121 2/20 0.44
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PTPN1 P18031 1/20 0.43
KDM4C Q9H3R0 1/20 0.42
HDAC4 P56524 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11248496 0.82 ACMSD (0.61) ACMSDKMODHODHTBK1IKBKE
SCHEMBL8867391 0.76 DHODH (0.51) ACMSDKMODHODHTBK1SERPINE1
SCHEMBL6617336 0.76 ALDH1A1 (0.48) ACMSDKMODHODHHIF1ATDP1
SCHEMBL31672133 0.76 ALDH1A1 (0.48) ACMSDKMODHODHHIF1ATDP1
SCHEMBL23374556 0.76 ACMSD (0.75) ACMSDKMODHODHTBK1IKBKE
SCHEMBL4827205 0.76 KMO (0.51) ACMSDKMODHODHNR4A1NR4A2
SCHEMBL31498321 0.75 CYP1A2 (0.50) KMOKDM4EHTTSMN1; SMN2HDAC4
SCHEMBL31498320 0.75 KMO (0.42) ACMSDKMOKDM4EHTTSMN1; SMN2
SCHEMBL7612713 0.74 ALDH1A1 (0.50) ACMSDKMODHODHHIF1ATDP1
Naphthoic Acid SCHEMBL30525212 0.73 NR4A1 (0.88) NR4A1NR4A2NR4A3KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075416-A Suspending methanesulfonic acid and aromatic acid in aliphatic solvent, slowly adding unsaturated aromatic hydrocarbon RUTGERSWERKE AG (DE) 1991-12-24 US disclosed