Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377737 | 1.00 | TLR8 (0.43) | TLR8PTGS2HTR2ACYP3A4TP53 | |
| SCHEMBL5372853 | 0.98 | TLR8 (0.41) | TLR8PTGS2HTR2ACYP3A4TP53 | |
| SCHEMBL831156 | 0.92 | SKP2 (0.41) | TLR8TYRHTT | |
| SCHEMBL14003767 | 0.90 | PTGS2 (0.53) | TLR8PTGS2HTR2ACYP3A4TP53 | |
| SCHEMBL5377222 | 0.88 | SKP2 (0.39) | TLR8TYRHTT | |
| SCHEMBL3945176 | 0.86 | POLB (0.40) | TLR8TYRHTT | |
| SCHEMBL3937871 | 0.86 | POLB (0.40) | TLR8TYRHTT | |
| SCHEMBL7549595 | 0.83 | SKP2 (0.47) | TLR8CYP3A4TP53MAPTTYR | |
| SCHEMBL1100124 | 0.83 | DHFR (0.41) | HTTSHBG | |
| SCHEMBL174991 | 0.81 | TLR8 (0.43) | TLR8PTGS2HTR2ACYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037862-A | Excellent mechanical stability in printing | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1991-08-06 | — | — | US | disclosed |