Isophthalic Acid

Isophthalic Acid

SCHEMBL9766398

O=C(O)c1cc([Na])cc(C(=O)O)c1S(=O)(=O)O.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 2/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
CA12 O43570 1/20 0.42
CA6 P23280 1/20 0.42
CYP2D6 P10635 1/20 0.41
KDM4E B2RXH2 1/20 0.40
KMO O15229 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PTPN1 P18031 1/20 0.39
F2 P00734 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
UNG P13051 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL4453159 0.88 TSHR (0.43) CA1CA2CA9LCKFYN
Isophthalic Acid SCHEMBL28784194 0.86 ALOX15 (0.49) CA1CA2CA9LCKFYN
SCHEMBL63328 0.86 CYP2D6 (0.42) CA1CA2CA9LCKFYN
SCHEMBL8899334 0.84 ALDH1A1 (0.43) CA1CA2CA9LCKFYN
Terephthalic Acid SCHEMBL17457900 0.83 PTPN1 (0.49) CA1CA2CA9LCKFYN
SCHEMBL19304512 0.78 PTPN1 (0.44) CA1CA2CA9LCKFYN
Terephthalic Acid SCHEMBL6654997 0.78 CYP2C19 (0.44) CA1CA2CA9LCKFYN
Isophthalic Acid SCHEMBL17457903 0.77 HDAC3 (0.42) CA1CA2CA9LCKFYN
SCHEMBL8899330 0.77 ALDH1A1 (0.38) LCKFYNCYP2D6KDM4EHPGD
SCHEMBL27723018 0.77 CYP2D6 (0.36) LCKFYNCYP2D6KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006598-A Made from isophthalic and 5-sulfoisophthalic acids, 1,4-cyclohexanedimethanol and diethylene glycol EASTMAN KODAK COMPANY (US) 1991-04-09 US disclosed
US-4148779-A COPOLYESTER CONTAINING METAL SULFONATE GROUPS EASTMAN KODAK COMPANY (US) 1979-04-10 US disclosed