Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943130 | 0.91 | CYP3A4 (0.44) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL179736 | 0.86 | CYP3A4 (0.52) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL9438205 | 0.85 | LMNA (0.43) | CYP3A4L3MBTL1ALDH1A1TDP1PRSS1 | |
| SCHEMBL9438365 | 0.85 | LMNA (0.43) | CYP3A4L3MBTL1ALDH1A1TDP1PRSS1 | |
| SCHEMBL5161833 | 0.85 | LMNA (0.43) | CYP3A4L3MBTL1ALDH1A1TDP1PRSS1 | |
| SCHEMBL10533559 | 0.81 | CYP3A4 (0.47) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL28943056 | 0.79 | OPRM1 (0.40) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL17780067 | 0.79 | CYP3A4 (0.52) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL19123571 | 0.79 | CYP3A4 (0.50) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR | |
| SCHEMBL27870950 | 0.78 | CYP3A4 (0.46) | CYP3A4L3MBTL1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4995997-A | Containing aromatic amine | YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0388320-A1 | Antibacterial water-soluble cutting fluids resistant to yeast-like fungi | YUSHIRO CHEMICAL INDUSTRY CO. LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |