SCHEMBL9766827

SCHEMBL9766827

COC(=O)c1cc(F)ccc1S(=O)(=O)N=C=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.42
KCNH2 Q12809 1/20 0.40
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CA2 P00918 3/20 0.38
CA1 P00915 1/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
ACLY P53396 1/20 0.36
F2 P00734 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9766751 0.83 ABL1 (0.47) CDK1SLC6A4SLC6A3CA2CA1
SCHEMBL10838076 0.80 ACLY (0.47) SLC6A4SLC6A3CA2CA1CA5A
SCHEMBL6228820 0.80 CA1 (0.59) CA2CA1CA5ACA9NPC1
SCHEMBL1110811 0.79 CDK1 (0.48) CDK1KCNH2SLC6A4SLC6A3CA2
SCHEMBL10839608 0.78 XDH (0.43) CDK1CA2CA1CA5ACA9
SCHEMBL22827956 0.78 CDK1 (0.47) CDK1KCNH2SLC6A4SLC6A3CA2
SCHEMBL11374760 0.76 KDM4E (0.50) CA2CA1CA5ACA9SMN1; SMN2
SCHEMBL6534338 0.75 KDM4E (0.44) CA2CA1CA5ACA9NPC1
SCHEMBL6012073 0.75 CA2 (0.40) CDK1CA2CA1CA5ACA9
SCHEMBL11334105 0.75 ABL1 (0.50) SLC6A4SLC6A3CA2CA1CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5071470-A Pre- or postemergence BASF AKTIENGESELLSCHAFT (DE) 1991-12-10 US disclosed