Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740356 | 0.84 | THRB (0.64) | THRBMAPTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL11319149 | 0.81 | MAPT (0.75) | MAPTCYP1A2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL8958338 | 0.81 | THRB (0.52) | THRBMAPTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL7559043 | 0.80 | MAPT (0.72) | MAPTCYP1A2CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL7998280 | 0.79 | ADRA2A (0.50) | THRBMAPTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL7149998 | 0.79 | MAPT (0.71) | MAPTHTTKAT2BALDH1A1SYK | |
| SCHEMBL5605010 | 0.79 | ADRA2A (0.50) | THRBMAPTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL27520329 | 0.79 | ADRA2A (0.50) | THRBMAPTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL5604580 | 0.79 | ALDH1A1 (0.59) | THRBMAPTCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL10381587 | 0.79 | ADRA2A (0.50) | THRBMAPTCYP1A2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4995997-A | Containing aromatic amine | YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| EP-0388320-A1 | Antibacterial water-soluble cutting fluids resistant to yeast-like fungi | YUSHIRO CHEMICAL INDUSTRY CO. LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |