Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767270 | 0.89 | POLB (0.39) | MAPTPOLBAKR1B1MEN1KMT2A | |
| SCHEMBL5695096 | 0.82 | MAOB (0.38) | MAOBESPL1MAPTCYP19A1SMN1; SMN2 | |
| SCHEMBL9767624 | 0.79 | MAOB (0.35) | MAOBESPL1MAPTCYP19A1SMN1; SMN2 | |
| SCHEMBL9767628 | 0.79 | MAOB (0.35) | MAOBESPL1MAPTCYP19A1SMN1; SMN2 | |
| SCHEMBL9767027 | 0.78 | TSHR (0.38) | MAPTSMN1; SMN2AKR1B1MEN1KMT2A | |
| SCHEMBL9767647 | 0.70 | ESPL1 (0.43) | ESPL1MAPTSMN1; SMN2POLBAKR1B1 | |
| SCHEMBL980916 | 0.69 | MAOB (0.45) | MAOBESPL1MAPTCYP19A1RAB9A | |
| SCHEMBL6978574 | 0.69 | HSP90AA1 (0.36) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL6736201 | 0.68 | MAOB (0.63) | MAOBALDH1A1 | |
| SCHEMBL27537102 | 0.68 | AKR1B1 (0.45) | ESPL1MAPTCYP19A1AKR1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072006-A | Chemical intermeidate; hypotensive agents, muscle relaxants | RECHERCHE SYNTEX FRANCE S.A. (FR) | 1991-12-10 | — | — | US | disclosed |
| US-4997846-A | Smooth muscle relaxants, hypotensives | RESEARCHE SYNTEX FRANCE, S.A. (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0377966-A2 | Novel benzopyranylpyrrolinone derivatives | RECHERCHE SYNTEX FRANCE SA (FR) | 1990-07-18 | — | — | EP | disclosed |