Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyne SCHEMBL28045684 | 0.79 | CA2 (0.52) | TSHRGLASMN1; SMN2APPTDP1 | |
| SCHEMBL29419589 | 0.78 | CA2 (0.56) | TSHRGLASMN1; SMN2APPTDP1 | |
| SCHEMBL20509 | 0.78 | CA2 (0.56) | TSHRGLASMN1; SMN2APPTDP1 | |
| SCHEMBL811943 | 0.76 | MAPK1 (0.65) | TSHRGLASMN1; SMN2TUBB1TDP1 | |
| SCHEMBL1256865 | 0.76 | CA2 (0.54) | TSHRGLASMN1; SMN2APPTDP1 | |
| SCHEMBL29697819 | 0.76 | MAPK1 (0.65) | TSHRGLASMN1; SMN2TUBB1TDP1 | |
| SCHEMBL2811536 | 0.76 | CA2 (0.41) | TSHRSMN1; SMN2GAAMAPK1ALDH1A1 | |
| SCHEMBL14125145 | 0.76 | GAA (0.56) | TSHRGLASMN1; SMN2GAATDP1 | |
| SCHEMBL81131 | 0.74 | NQO2 (0.47) | TSHRGLASMN1; SMN2GAATDP1 | |
| SCHEMBL30970345 | 0.74 | NQO2 (0.47) | TSHRGLASMN1; SMN2GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409931-A1 | QUINUCLIDINE THERAPEUTIC AGENTS. | PFIZER (US) | 1991-01-30 | — | — | EP | disclosed |
| WO-1990005729-A1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER INC. (US) | 1990-05-31 | — | — | WO | disclosed |