Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970345 | 1.00 | NQO2 (0.47) | NQO2ALOX15MAPTTHRBNPC1 | |
| SCHEMBL17351634 | 0.98 | NQO2 (0.46) | NQO2ALOX15MAPTTHRBNPC1 | |
| SCHEMBL5327500 | 0.84 | MAPT (0.43) | NQO2ALOX15MAPTTHRBNPC1 | |
| SCHEMBL14499435 | 0.83 | PDGFRB (0.49) | NQO2ALOX15MAPTTHRBALDH1A1 | |
| SCHEMBL17151135 | 0.81 | PTGS2 (0.44) | NQO2MAPTTHRBNPC1RAB9A | |
| SCHEMBL29426969 | 0.81 | KDM4E (0.43) | NQO2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL5156534 | 0.81 | KDM4E (0.43) | NQO2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL29419589 | 0.80 | CA2 (0.56) | MAPTALDH1A1L3MBTL1TDP1ACHE | |
| SCHEMBL20509 | 0.80 | CA2 (0.56) | MAPTALDH1A1L3MBTL1TDP1ACHE | |
| SCHEMBL30760975 | 0.80 | ATM (0.43) | MAPTRAB9AALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 668 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119191946-B | Electrophilic cross-coupling method of aryl perfluoro butyl sulfonate and aryl bromide | 南京工业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-118955262-A | Direct cross-coupling method of pyridine ester and aryl bromide | 南京工业大学 | 2024-11-15 | — | — | CN | claimed |
| CN-116041153-B | Direct cross coupling method of aryl thioether and aryl bromine | 南京工业大学 | 2024-05-24 | — | — | CN | claimed |
| CN-116253623-B | Direct cross-coupling method of aryl fluorine sulfate and aryl bromine | 南京工业大学 | 2024-04-05 | — | — | CN | claimed |
| CN-114591128-B | Direct cross-coupling method of aryl sulfide salt and aryl bromide | 南京工业大学 | 2023-08-22 | — | — | CN | claimed |
| CN-116573994-A | Direct cross-coupling method of triazine ester and aryl bromide | 南京工业大学 | 2023-08-11 | — | — | CN | claimed |
| CN-116554009-A | Electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide | 南京工业大学 | 2023-08-08 | — | — | CN | claimed |
| CN-116283515-A | Direct cross coupling method of aryl fluoride and aryl bromide | 南京工业大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116253623-A | Direct cross-coupling method of aryl fluorine sulfate and aryl bromine | 南京工业大学 | 2023-06-13 | — | — | CN | claimed |
| CN-116041153-A | Direct cross coupling method of aryl thioether and aryl bromine | 南京工业大学 | 2023-05-02 | — | — | CN | claimed |
| CN-113387876-A | Nickel-catalyzed direct reduction cross-coupling method for heterocyclic phosphonium salt and aryl bromide and product | 南京工业大学 | 2021-09-14 | — | — | CN | claimed |
| EP-3692101-A1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | Alfa Instruments S.r.l. (IT) | 2020-08-12 | — | — | EP | claimed |
| WO-2019068935-A1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | ALFA INSTRUMENTS S.R.L. (IT) | 2019-04-11 | — | — | WO | claimed |
| US-9997714-B2 | Hole transport material | MERCK PATENT GMBH (DE) | 2018-06-12 | — | — | US | claimed |
| EP-2183239-B1 | SULFONAMIDES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-08-22 | — | — | EP | claimed |
| US-8153682-B2 | Sulfonamides as TRPM8 modulators | JANSSEN PHARMACEUTICA, NV (BE) | 2012-04-10 | — | — | US | claimed |
| EP-2183239-A1 | SULFONAMIDES AS TRPM8 MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2010-05-12 | — | — | EP | claimed |
| US-20090264474-A1 | SULFONAMIDES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-10-22 | — | — | US | claimed |
| WO-2009012430-A1 | SULFONAMIDES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-22 | — | — | WO | claimed |
| US-5008464-A | Anisole bromination | EAST SHORT CHEMICAL COMPANY (US) | 1991-04-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264474-A1 | SULFONAMIDES AS TRPM8 MODULATORS | TRPM8, TRPM5, TRPM2 | NQO2 1677/4885ALOX15 3450/4885MAPT 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.