Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.60 |
| ▸ | MEN1 | O00255 | 12/20 | 0.60 |
| ▸ | POLB | P06746 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9767814 | 0.85 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1THRBKMT2AMEN1 | |
| SCHEMBL10981054 | 0.82 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1THRBKMT2AMEN1 | |
| SCHEMBL9767850 | 0.80 | RAB9A (0.56) | ALDH1A1L3MBTL1KMT2AMEN1MAPT | |
| SCHEMBL9768093 | 0.78 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1THRBKMT2AMEN1 | |
| SCHEMBL4024692 | 0.76 | KMT2A (1.00) | ALDH1A1L3MBTL1THRBKMT2AMEN1 | |
| SCHEMBL4024688 | 0.76 | KMT2A (1.00) | ALDH1A1L3MBTL1THRBKMT2AMEN1 | |
| SCHEMBL8290471 | 0.72 | KMT2A (1.00) | ALDH1A1L3MBTL1THRBKMT2AMEN1 | |
| SCHEMBL9767906 | 0.71 | L3MBTL1 (0.52) | ALDH1A1L3MBTL1THRBKMT2AMEN1 | |
| SCHEMBL11473956 | 0.70 | ELANE (0.46) | ALDH1A1L3MBTL1KMT2APOLBRAB9A | |
| SCHEMBL10653589 | 0.68 | HCAR2 (0.62) | ALDH1A1L3MBTL1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |