SCHEMBL9767929

SCHEMBL9767929

[CH2]C=CC(CC)(c1ccccc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47
KIF11 P52732 2/20 0.41
MAOB P27338 2/20 0.36
KDM1A O60341 1/20 0.36
MAOA P21397 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
CYP19A1 P11511 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRL1 P41146 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
BACE1 P56817 2/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9767970 0.89 KCNN4 (0.38) ALDH1A1TSHROPRM1CYP3A4CYP2D6
SCHEMBL9767862 0.75 KCNN4 (0.35) ALDH1A1TSHRKIF11OPRM1RAB9A
SCHEMBL9768017 0.75 MMP1 (0.33) ALDH1A1
SCHEMBL17935605 0.72 ALDH1A1 (0.61) ALDH1A1TSHRKIF11TRPV6CYP19A1
SCHEMBL9767832 0.71 KIF11 (0.45) ALDH1A1KIF11KDM1APPARGPPARA
SCHEMBL17935607 0.71 ALDH1A1 (0.58) ALDH1A1TSHRKIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL14121438 0.71 TSHR (0.93) ALDH1A1TSHRKIF11TRPV6CYP19A1
Trifluoromethylbenzene SCHEMBL1830622 0.71 TSHR (0.93) ALDH1A1TSHRKIF11TRPV6CYP19A1
SCHEMBL1148767 0.70 KCNN4 (0.40) ALDH1A1TSHRKIF11OPRM1NPC1
Trifluoromethylbenzene SCHEMBL3392949 0.69 TSHR (0.70) ALDH1A1TSHRKIF11TRPV6SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5022914-A Pre- and post-emergence; broad leaf plants; rice BASF AKTIENGESELLSCHAFT (DE) 1991-06-11 US disclosed