Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705641 | 0.78 | TDP1 (0.39) | TSPOALDH1A1TSHRTDP1SLC6A4 | |
| SCHEMBL8825997 | 0.76 | TSPO (0.47) | TSPOTSHRHSD17B10SLC6A4SLC6A2 | |
| SCHEMBL5496325 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL8858287 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL11678305 | 0.73 | LTA4H (0.51) | TSPOSLC6A4SLC6A2HTTL3MBTL1 | |
| SCHEMBL27580719 | 0.72 | ALDH1A1 (0.63) | CHRNA7CHRNA10CHRNA9ALDH1A1MAPK1 | |
| SCHEMBL14130020 | 0.72 | ALDH1A1 (0.63) | CHRNA7CHRNA10CHRNA9ALDH1A1MAPK1 | |
| SCHEMBL15489413 | 0.72 | MAPT (0.53) | ALDH1A1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL972448 | 0.71 | ALDH1A1 (0.61) | ALDH1A1MAPK1TSHRHSD17B10TDP1 | |
| SCHEMBL12735263 | 0.71 | ALDH1A1 (0.61) | ALDH1A1MAPK1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037967-A | Monoazo couplers for disperse dyes | CIBA-GEIGY CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-4910299-A | Azo group attached to phenyl ring | CIBA-GEIGY CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |