Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15528812 | 0.82 | MAPK1 (0.71) | KDM4EKMT2ANPC1RAB9APOLB | |
| SCHEMBL28942208 | 0.79 | TRPA1 (0.59) | KDM4EKMT2ARAB9AMEN1L3MBTL1 | |
| SCHEMBL13936398 | 0.76 | DHODH (0.64) | KDM4EKMT2APOLBMAPTMEN1 | |
| SCHEMBL7427911 | 0.75 | ALDH1A1 (0.60) | KDM4EKMT2APOLBMAPTMEN1 | |
| SCHEMBL29367052 | 0.73 | DHODH (0.62) | KDM4EKMT2ANPC1RAB9APOLB | |
| SCHEMBL346345 | 0.73 | DHODH (0.62) | KDM4EKMT2ANPC1RAB9APOLB | |
| SCHEMBL4315667 | 0.72 | PTPN1 (0.64) | KMT2APOLBMEN1ALDH1A1CFD | |
| SCHEMBL30583240 | 0.72 | PTPN1 (0.64) | KMT2APOLBMEN1ALDH1A1CFD | |
| SCHEMBL11537231 | 0.72 | DHODH (0.60) | KDM4EKMT2ANPC1RAB9APOLB | |
| SCHEMBL9767875 | 0.71 | L3MBTL1 (0.49) | KDM4EKMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0153850-B1 | ACRYLAMIDOBENZOIC ACID DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |