Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CFD | P00746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432076 | 0.85 | KDM4E (0.59) | ALDH1A1L3MBTL1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4040223 | 0.80 | ALDH1A1 (0.82) | ALDH1A1L3MBTL1CFDKDM4ELMNA | |
| SCHEMBL13936398 | 0.79 | DHODH (0.64) | ALDH1A1L3MBTL1CFDKDM4ELMNA | |
| SCHEMBL8437112 | 0.79 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1CFDKDM4ELMNA | |
| SCHEMBL8485409 | 0.78 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1CFDKDM4ELMNA | |
| SCHEMBL29367052 | 0.77 | DHODH (0.62) | ALDH1A1CFDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL346345 | 0.77 | DHODH (0.62) | ALDH1A1CFDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL30583240 | 0.76 | PTPN1 (0.64) | ALDH1A1CFDLMNAKMT2ADHODH | |
| SCHEMBL4315667 | 0.76 | PTPN1 (0.64) | ALDH1A1CFDLMNAKMT2ADHODH | |
| SCHEMBL28942208 | 0.76 | TRPA1 (0.59) | ALDH1A1L3MBTL1CFDKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |