Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300277 | 0.79 | ATF4 (0.58) | ATF4RAB9APOLBMAPTHPGD | |
| SCHEMBL10446002 | 0.78 | ATF4 (0.56) | ATF4RAB9APOLBMAPTHPGD | |
| SCHEMBL9768219 | 0.77 | GSK3B (0.44) | POLBMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL23630306 | 0.76 | SSTR1 (0.46) | POLBMEN1KMT2ATSHRCYP2C9 | |
| SCHEMBL11296862 | 0.75 | OPRM1 (0.49) | POLBMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL9768235 | 0.75 | SSTR1 (0.48) | RAB9APOLBMEN1KMT2AMAOA | |
| SCHEMBL2699816 | 0.73 | MEN1 (0.67) | RAB9APOLBMAPTHPGDMEN1 | |
| SCHEMBL11440981 | 0.72 | MAPT (0.60) | ATF4RAB9APOLBMAPTHPGD | |
| SCHEMBL9578176 | 0.71 | ATF4 (0.52) | ATF4RAB9APOLBMAPTHPGD | |
| SCHEMBL3328507 | 0.71 | ALDH1A1 (0.52) | ATF4RAB9APOLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988383-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0384246-A2 | Cyclopropyl-hydroxyethyl-azolyl derivatives | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |