Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916844 | 0.83 | ATF4 (0.47) | ATF4RAB9AMAPTPOLBHPGD | |
| SCHEMBL9300277 | 0.81 | ATF4 (0.58) | ATF4RAB9AMAPTPOLBHPGD | |
| SCHEMBL9578176 | 0.80 | ATF4 (0.52) | ATF4RAB9AMAPTPOLBHPGD | |
| SCHEMBL9768233 | 0.78 | ATF4 (0.54) | ATF4RAB9AMAPTPOLBHPGD | |
| SCHEMBL9768195 | 0.76 | ABCB11 (0.54) | ATF4MAPTPOLBL3MBTL1MEN1 | |
| SCHEMBL20610371 | 0.75 | ATF4 (0.78) | ATF4RAB9AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL3370944 | 0.74 | PTGS2 (0.56) | ATF4RAB9AMAPTPOLBHPGD | |
| SCHEMBL3913180 | 0.74 | PTGS2 (0.60) | ATF4RAB9AMAPTPOLBHPGD | |
| SCHEMBL19569414 | 0.74 | ATF4 (0.75) | ATF4RAB9AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL11440981 | 0.74 | MAPT (0.60) | ATF4RAB9AMAPTPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384246-A2 | Cyclopropyl-hydroxyethyl-azolyl derivatives | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |