Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28535211 | 0.84 | ADRA2A (0.62) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL6399196 | 0.80 | ADRB3 (0.45) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL6246174 | 0.75 | ADRB1 (0.40) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL6259255 | 0.72 | ADRB2 (0.55) | ADRB2ADRB1 | |
| SCHEMBL6258471 | 0.70 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6259212 | 0.70 | ADRB2 (0.57) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6262196 | 0.70 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL9768329 | 0.70 | ADRB2 (0.43) | ADRB2ADRB1LMNADRD3 | |
| SCHEMBL28067345 | 0.67 | ADRB2 (0.69) | ADRA2AADRA1AADRB2ADRB1ADRB3 | |
| SCHEMBL25100811 | 0.66 | MAPT (0.69) | ADRA2AADRA2BADRA2CADRA1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047592-A | Selective hydrogenolysis process | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |