SCHEMBL28535211

SCHEMBL28535211

CNC[C@H](O)c1ccc(O)c(O)c1OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 6/20 0.62
ADRA2B P18089 6/20 0.62
ADRA2C P18825 6/20 0.62
ADRA1A P35348 3/20 0.62
ADRB1 P08588 5/20 0.46
ADRB3 P13945 4/20 0.46
ADRB2 P07550 4/20 0.46
TDP1 Q9NUW8 4/20 0.46
KDM4E B2RXH2 4/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HIF1A Q16665 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CYP2D6 P10635 1/20 0.46
DRD2 P14416 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9768276 0.84 ADRA2A (0.44) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL1819427 0.81 ADRA2A (0.62) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL6399196 0.80 ADRB3 (0.45) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL9767993 0.78 ADRA2A (0.68) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL1461292 0.78 ADRA2A (0.68) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL6246174 0.78 ADRB1 (0.40) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL9768011 0.77 ADRA2A (1.00) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL2760850 0.77 ADRA2A (0.66) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL29278698 0.77 ADRA2A (0.66) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL29852847 0.77 ADRA2A (1.00) ADRA2AADRA2BADRA2CADRA1AADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112266330-B Methoxyarenol derivative, immunogen, anti-methoxyadrol specific antibody, preparation method and application thereof 长沙博源医疗科技有限公司 2023-02-24 CN disclosed
CN-114354938-A Vanilmandelic acid homogeneous enzyme immunoassay reagent based on brominated derivatives and preparation method thereof 苏州博源医疗科技有限公司 2022-04-15 CN disclosed
CN-112266330-A Methoxy adrenaline derivative, immunogen, anti-methoxy adrenaline specific antibody, preparation method and application thereof 湖南苏阳医疗科技有限公司 2021-01-26 CN disclosed