Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768337 | 0.86 | GRIN2B (0.51) | GRIN2BDRD2HTR1AHTR2AKDM1A | |
| SCHEMBL10838656 | 0.82 | GRIN2B (0.51) | GRIN2BDRD2HTR1AHTR2ADRD4 | |
| SCHEMBL27076186 | 0.81 | GRIN2B (0.56) | GRIN2BDRD2HTR1AHTR2AKDM1A | |
| SCHEMBL27076422 | 0.81 | GRIN2B (0.56) | GRIN2BDRD2HTR1AHTR2AKDM1A | |
| SCHEMBL27076244 | 0.81 | GRIN2B (0.56) | GRIN2BDRD2HTR1AHTR2AKDM1A | |
| SCHEMBL27076418 | 0.81 | GRIN2B (0.56) | GRIN2BDRD2HTR1AHTR2AKDM1A | |
| SCHEMBL29960317 | 0.81 | GRIN2B (0.56) | GRIN2BDRD2HTR1AHTR2AKDM1A | |
| SCHEMBL29961050 | 0.81 | GRIN2B (0.56) | GRIN2BDRD2HTR1AHTR2AKDM1A | |
| SCHEMBL27076177 | 0.81 | GRIN2B (0.56) | GRIN2BDRD2HTR1AHTR2AKDM1A | |
| SCHEMBL8301786 | 0.78 | HTR1A (0.53) | GRIN2BDRD2HTR1AHTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034401-A | Cardiovascular disorders or antiischemia agents | SYNTHELABO (FR) | 1991-07-23 | — | — | US | claimed |
| US-5034401-A | Cardiovascular disorders or antiischemia agents | SYNTHELABO (FR) | 1991-07-23 | — | — | US | disclosed |