Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HTR5A | P47898 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.59 |
| ▸ | HTR3B | O95264 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | HTR3A | P46098 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.59 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099691 | 0.86 | MTNR1B (0.53) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| SCHEMBL9643856 | 0.82 | HTR1A (0.74) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| SCHEMBL19284691 | 0.82 | HTR1A (0.59) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| SCHEMBL19284664 | 0.82 | TSHR (0.59) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| SCHEMBL3096747 | 0.81 | MTNR1B (0.48) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| Hydrochloric Acid SCHEMBL7203515 | 0.81 | KDM4E (0.75) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| SCHEMBL1876619 | 0.79 | NCF1 (0.69) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| SCHEMBL569714 | 0.79 | HTR1A (0.69) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| SCHEMBL156749 | 0.78 | HTR1A (0.54) | HTR1ATSHRHTR5AHSD17B10HTR3E | |
| SCHEMBL7491687 | 0.77 | NCF1 (0.67) | HTR1ATSHRHTR5AHSD17B10HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034401-A | Cardiovascular disorders or antiischemia agents | SYNTHELABO (FR) | 1991-07-23 | — | — | US | disclosed |