Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATF4 | P18848 | 2/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362200 | 0.73 | ATF4 (0.40) | ABCB11LMNAMAPTMAPK1CYP1A2 | |
| SCHEMBL954683 | 0.72 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1MEN1 | |
| Rac-Etomoxir SCHEMBL15256787 | 0.72 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1MEN1 | |
| Etomoxir SCHEMBL49075 | 0.72 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1MEN1 | |
| Rac-Etomoxir SCHEMBL681359 | 0.72 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL9768195 | 0.71 | ABCB11 (0.54) | ABCB11LMNAMAPTMAPK1MEN1 | |
| Etomoxir SCHEMBL12813827 | 0.71 | MAPT (0.98) | ABCB11LMNAMAPTMAPK1MEN1 | |
| Etomoxir SCHEMBL5883664 | 0.71 | MAPT (0.98) | ABCB11LMNAMAPTMAPK1MEN1 | |
| SCHEMBL2818420 | 0.70 | MAPT (0.53) | ABCB11LMNAMAPTMAPK1MEN1 | |
| Rac-Etomoxir SCHEMBL2141141 | 0.70 | MAPT (0.95) | ABCB11LMNAMAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988383-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0384246-A2 | Cyclopropyl-hydroxyethyl-azolyl derivatives | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |