SCHEMBL9768376

SCHEMBL9768376

O=C(ON1CCC(Cc2ccc(F)cc2)CC1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
POLB P06746 1/20 0.54
CCR3 P51677 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5206501 0.81 OPRM1 (0.49) MEN1KMT2APOLBCCR3
SCHEMBL13108352 0.80 CYP2C9 (0.64) MEN1KMT2APOLB
SCHEMBL27816805 0.79 MEN1 (0.47) MEN1KMT2APOLB
SCHEMBL27781385 0.77 KMT2A (0.46) RAB9AMEN1KMT2APOLB
SCHEMBL18507156 0.77 RAB9A (0.47) RAB9AMEN1KMT2A
SCHEMBL26418689 0.76 CARM1 (0.44) RAB9AMEN1KMT2A
SCHEMBL5373262 0.75 ALDH1A1 (0.56) RAB9AMEN1KMT2ACCR3
SCHEMBL2925616 0.75 MEN1 (0.60) MEN1KMT2APOLB
SCHEMBL3455691 0.75 HTT (0.69) MEN1KMT2APOLB
SCHEMBL18821943 0.74 KMT2A (0.46) RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034401-A Cardiovascular disorders or antiischemia agents SYNTHELABO (FR) 1991-07-23 US disclosed