Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731016 | 0.74 | TSHR (0.48) | ALDH1A1GLATDP1TSHRTP53 | |
| Ethylene SCHEMBL28194681 | 0.70 | ALDH1A1 (0.45) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL28460059 | 0.70 | PKM (0.51) | ALDH1A1TDP1TSHRTP53MAPT | |
| SCHEMBL9234580 | 0.70 | PKM (0.51) | ALDH1A1TDP1TSHRTP53MAPT | |
| SCHEMBL9618007 | 0.70 | PKM (0.51) | ALDH1A1TDP1TSHRTP53MAPT | |
| SCHEMBL3916038 | 0.70 | ESR1 (0.41) | ALDH1A1MAPTESR1ESR2KMT2A | |
| SCHEMBL6224406 | 0.70 | ESR1 (0.38) | ALDH1A1MAPTESR1ESR2MAPK1 | |
| SCHEMBL21715829 | 0.70 | SMN1; SMN2 (0.44) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL31140019 | 0.70 | SMN1; SMN2 (0.44) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL9234674 | 0.70 | AGXT (0.44) | ALDH1A1GLATDP1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011918-A | Siloxane Derivatives Are Useful In Glass Fiber Sizing Compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4929670-A | GLASS SIZING COMPOSITIONS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4839449-A | SIZING COMPOSITION FOR GLASS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |