Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618007 | 1.00 | PKM (0.51) | PKMIDO1AGXTCA1CA2 | |
| 1,4-Dimethoxybenzene SCHEMBL11135429 | 0.87 | PKM (0.58) | PKMCA1CA2DRD4TP53 | |
| SCHEMBL731016 | 0.87 | TSHR (0.48) | TP53MAPTHPGDTSHRMEN1 | |
| SCHEMBL732255 | 0.84 | TDP1 (0.59) | PKMDRD4TP53MAPTHPGD | |
| SCHEMBL18548800 | 0.84 | TDP1 (0.59) | PKMDRD4TP53MAPTHPGD | |
| SCHEMBL5854038 | 0.83 | TDP1 (0.47) | PKMIDO1AGXTCA1CA2 | |
| Glycidol SCHEMBL19463580 | 0.83 | CA1 (0.45) | PKMIDO1AGXTCA1CA2 | |
| SCHEMBL7238655 | 0.83 | PKM (0.49) | PKMDRD4TP53MAPTHPGD | |
| SCHEMBL16614412 | 0.83 | TDP1 (0.47) | PKMIDO1AGXTCA1CA2 | |
| Mequinol SCHEMBL3679208 | 0.83 | PKM (0.51) | PKMTP53MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | disclosed |
| CN-116037208-A | Preparation method of simple-synthesized high-stability silver cluster-based metal-organic framework | 山东理工大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-108779082-B | Contrast agents | 伯拉考成像股份公司 | 2022-08-02 | — | — | CN | disclosed |
| EP-3442949-B1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2022-06-08 | — | — | EP | disclosed |
| US-11007283-B2 | Contrast agents | BRACCO IMAGING S.P.A. (IT) | 2021-05-18 | — | — | US | disclosed |
| CN-111263783-A | Polymeric dispersants from phenyl glycidyl ethers | 斯泰潘公司 | 2020-06-09 | — | — | CN | disclosed |
| US-20190167819-A1 | CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2019-06-06 | — | — | US | disclosed |
| EP-3442949-A1 | CONTRAST AGENTS | Bracco Imaging S.p.A (IT) | 2019-02-20 | — | — | EP | disclosed |
| CN-108779082-A | CONTRAST AGENTS | 伯拉考成像股份公司 | 2018-11-09 | — | — | CN | disclosed |
| WO-2017178301-A1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-10-19 | — | — | WO | disclosed |
| EP-2935278-B1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | NOVARTIS AG (CH) | 2017-03-15 | — | — | EP | disclosed |
| US-9359381-B2 | Tricyclic compounds for inhibiting the CFTR channel | NOVARTIS AG (CH) | 2016-06-07 | — | — | US | disclosed |
| US-20150336986-A1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | NOVARTIS AG (CH) | 2015-11-26 | — | — | US | disclosed |
| EP-2935278-A1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | Novartis AG (CH) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014097148-A9 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | NOVARTIS AG (CH) | 2015-02-19 | — | — | WO | disclosed |
| WO-2014097148-A1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | NOVARTIS AG (CH) | 2014-06-26 | — | — | WO | disclosed |
| US-20140171417-A1 | TRICYCLIC COMPOUNDS | NOVARTIS AG (CH) | 2014-06-19 | — | — | US | disclosed |
| EP-0664316-A1 | Polycarbonate composition having improved resistance to gamma-ray radiation | TEIJIN LIMITED (JP) | 1995-07-26 | — | — | EP | disclosed |
| EP-0264114-A1 | Alpha-[(phenylmethoxy)methyl]pyridine-alkanol derivatives | G.D. Searle & Co. (US) | 1988-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336986-A1 | TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL | CFTR, SLC26A4, ABCB11 | PKM 2989/4885IDO1 4562/4885AGXT 2017/4885 |
| US-11007283-B2 | Contrast agents | PHOSPHO1, ITPA, PPIP5K2 | PKM 2503/4885IDO1 3324/4885AGXT 3729/4885 |
| US-20140171417-A1 | TRICYCLIC COMPOUNDS | SLC10A1, CYP11B2, CYP11B1 | PKM 824/4885IDO1 2838/4885AGXT 1099/4885 |
| US-20190167819-A1 | CONTRAST AGENTS | PHOSPHO1, ITPA, PPIP5K2 | PKM 2503/4885IDO1 3324/4885AGXT 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.