Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381574 | 1.00 | TSHR (0.47) | TSHRALDH1A1CYP3A4NPC1TDP1 | |
| SCHEMBL28694899 | 0.91 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10ALOX15 | |
| SCHEMBL4212396 | 0.88 | TSHR (0.53) | TSHRALDH1A1NPC1TDP1L3MBTL1 | |
| SCHEMBL29635213 | 0.88 | ALDH1A1 (0.56) | TSHRALDH1A1CYP3A4NPC1TDP1 | |
| SCHEMBL1003784 | 0.87 | TSHR (0.52) | TSHRALDH1A1NPC1TDP1L3MBTL1 | |
| SCHEMBL4210618 | 0.87 | TSHR (0.52) | TSHRALDH1A1NPC1TDP1L3MBTL1 | |
| SCHEMBL4208157 | 0.87 | TSHR (0.52) | TSHRALDH1A1NPC1TDP1L3MBTL1 | |
| SCHEMBL16714063 | 0.87 | NPC1 (0.47) | TSHRALDH1A1NPC1L3MBTL1HSD17B10 | |
| SCHEMBL6205138 | 0.82 | LMNA (0.47) | NPC1TDP1L3MBTL1LMNA | |
| SCHEMBL3677102 | 0.81 | ALOX5 (0.44) | TSHRALDH1A1TDP1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994297-A | Method of using fast pyrolysis liquids as liquid smoke | ENSYN ENGINEERING ASSOCIATES, INC. (CA) | 1991-02-19 | — | — | US | disclosed |
| US-4876108-A | HEATING GROUND WOOD WITHOUT OXYGEN, COOLING, EXTRACTING WITH WATER | ENSYN ENGINEERING ASSOCIATES INC. (CA) | 1989-10-24 | — | — | US | disclosed |