Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.43 |
| ▸ | WNT3A | P56704 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3549198 | 0.85 | LMNA (0.49) | LMNAGAACTNNB1WNT3AL3MBTL1 | |
| SCHEMBL1405144 | 0.84 | LMNA (0.58) | LMNAGAACTNNB1WNT3AL3MBTL1 | |
| SCHEMBL9768560 | 0.82 | TSHR (0.47) | LMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL29381574 | 0.82 | TSHR (0.47) | LMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL6675290 | 0.78 | LMNA (0.51) | LMNAGAACTNNB1WNT3AL3MBTL1 | |
| SCHEMBL8232789 | 0.78 | CTNNB1 (0.57) | LMNAGAACTNNB1WNT3APTGS1 | |
| SCHEMBL10519876 | 0.77 | LMNA (0.58) | LMNAGAACTNNB1WNT3AL3MBTL1 | |
| SCHEMBL3430652 | 0.77 | LMNA (0.50) | LMNAGAACTNNB1WNT3ACNR2 | |
| SCHEMBL6206850 | 0.76 | LMNA (0.46) | LMNAGAACTNNB1WNT3AL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL28847475 | 0.76 | CTNNB1 (0.55) | LMNAGAACTNNB1WNT3APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534693-A2 | 1, 3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2005-06-01 | — | — | EP | claimed |
| WO-2004022523-A2 | 1, 3-DIAMINO-2-HYDROXYPROPANE PRODRUG DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2004-03-18 | — | — | WO | claimed |