Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913443 | 0.80 | ALDH1A1 (0.38) | ALDH1A1BCAT2POLBCA1CA2 | |
| SCHEMBL7054824 | 0.80 | ALDH1A1 (0.38) | ALDH1A1BCAT2POLBCA1CA2 | |
| SCHEMBL3759621 | 0.78 | CA2 (0.50) | CA1CA2CA4CA6 | |
| SCHEMBL2225465 | 0.78 | CYP1A2 (0.40) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8106699 | 0.75 | LOX (0.47) | ALDH1A1BCAT2CA1CA2CA4 | |
| SCHEMBL10411478 | 0.75 | CYP3A4 (0.50) | ALDH1A1BCAT2POLBCA1CA2 | |
| SCHEMBL26116950 | 0.74 | ALDH1A1 (0.67) | ALDH1A1BCAT2POLBCA1CA2 | |
| SCHEMBL21965036 | 0.74 | BCAT2 (0.38) | ALDH1A1BCAT2POLBCA1CA2 | |
| SCHEMBL11410987 | 0.71 | CA2 (0.47) | ALDH1A1POLBCA1CA2KDM4E | |
| SCHEMBL1542687 | 0.70 | CA1 (0.62) | ALDH1A1BCAT2POLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4011208-A | 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES | SANDOZ LTD. (CH) | 1977-03-08 | — | — | US | claimed |
| US-5053302-A | Photosensitivity, durability | FUJI PHOTO FILM CO., LTD. (JP) | 1991-10-01 | — | — | US | disclosed |
| US-4011208-A | 3-CYANO OR ACYL-4-ARYL-5-ARYLAZO-6-HYDROXYPYRIDONE-2 DYES | SANDOZ LTD. (CH) | 1977-03-08 | — | — | US | disclosed |