Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16052491 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GLACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL16052494 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GLACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL5422256 | 0.69 | ALDH1A1 (0.43) | ALDH1A1GLACHRNB2CHRNA4TP53 | |
| Ammonia Solution, Strong SCHEMBL28932670 | 0.69 | CHRNB2 (0.51) | ALDH1A1GLACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19478450 | 0.68 | CHRNB2 (0.57) | ALDH1A1GLACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19478474 | 0.68 | CHRNB2 (0.57) | ALDH1A1GLACHRNB2CHRNA4CHRNB4 | |
| SCHEMBL18133482 | 0.68 | CHRNB4 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL15065530 | 0.68 | KDM4E (0.33) | ALDH1A1CHRNB4CHRNA3HPGD | |
| SCHEMBL6786938 | 0.68 | KCNA3 (0.53) | ALDH1A1GLATDP1TP53TSHR | |
| SCHEMBL10586457 | 0.68 | ALDH1A1 (0.41) | ALDH1A1GLATDP1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011918-A | Siloxane Derivatives Are Useful In Glass Fiber Sizing Compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4929670-A | GLASS SIZING COMPOSITIONS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4839449-A | SIZING COMPOSITION FOR GLASS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |