Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150458 | 0.83 | MAOA (0.47) | MAOAPTGS1LMNASCN4AFFAR1 | |
| SCHEMBL15551593 | 0.80 | TAAR1 (0.46) | MAOAPTGS1LMNASCN4AFFAR1 | |
| SCHEMBL1509392 | 0.77 | SCN4A (0.43) | MAOAPTGS1LMNASCN4AFFAR1 | |
| SCHEMBL9534764 | 0.76 | LMNA (0.47) | LMNASCN4AADRB2KMT2AMEN1 | |
| SCHEMBL5134624 | 0.75 | SCN4A (0.53) | MAOAPTGS1LMNASCN4AFFAR1 | |
| SCHEMBL159889 | 0.74 | MAPT (0.43) | MAOAPTGS1LMNACYP2D6KMT2A | |
| SCHEMBL6956956 | 0.73 | RIPK1 (0.43) | MAOAPTGS1MAPK1 | |
| SCHEMBL11555241 | 0.71 | PTGS1 (0.40) | MAOAPTGS1LMNASCN4AMTNR1A | |
| SCHEMBL27917023 | 0.71 | LMNA (0.64) | MAOAPTGS1LMNAMTNR1AMTNR1B | |
| SCHEMBL17133871 | 0.71 | PTGS1 (0.40) | MAOAPTGS1LMNAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |