Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630021 | 0.90 | ALDH1A1 (0.46) | GAAL3MBTL1THRBATMNOS3 | |
| SCHEMBL4631015 | 0.89 | GAA (0.59) | GAAL3MBTL1THRBATMNOS3 | |
| SCHEMBL4756274 | 0.82 | CHRNB2 (0.42) | L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL5035936 | 0.79 | GAA (0.59) | GAAL3MBTL1THRBATMNOS3 | |
| SCHEMBL4524244 | 0.78 | HPGD (0.49) | THRBALDH1A1SMN1; SMN2MAPTRECQL | |
| SCHEMBL23041797 | 0.77 | GAA (0.62) | GAAL3MBTL1THRBATMNOS3 | |
| SCHEMBL10005159 | 0.77 | GAA (0.56) | GAAL3MBTL1THRBATMNOS3 | |
| SCHEMBL2978403 | 0.77 | GAA (0.56) | GAAL3MBTL1THRBATMNOS3 | |
| SCHEMBL23559762 | 0.77 | GAA (0.56) | GAAL3MBTL1THRBATMNOS3 | |
| SCHEMBL701943 | 0.77 | GAA (0.56) | GAAL3MBTL1THRBATMNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |