Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665701 | 0.76 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3MEN1MAPT | |
| SCHEMBL9664389 | 0.76 | SLC6A4 (0.72) | SLC6A4SLC6A2SLC6A3MEN1MAPT | |
| SCHEMBL23003619 | 0.73 | GABRA1 (0.41) | MEN1MAPTCYP2C9KMT2ALMNA | |
| SCHEMBL10903974 | 0.71 | IDO1 (0.38) | MEN1MAPTCYP2C9KMT2AALOX5 | |
| SCHEMBL9769205 | 0.70 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3KMT2ASMN1; SMN2 | |
| SCHEMBL5104539 | 0.69 | ALOX5 (0.42) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNB4 | |
| SCHEMBL17100358 | 0.69 | HTR1A (0.40) | SLC6A4SLC6A2SMN1; SMN2 | |
| SCHEMBL477486 | 0.68 | IDO1 (0.52) | SLC6A2SLC6A3LMNAALOX5SMN1; SMN2 | |
| SCHEMBL681660 | 0.68 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL11727401 | 0.66 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030647-A | Anti-inflammatory thienylbenzylamine compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1991-07-09 | — | — | US | disclosed |