Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28093895 | 0.91 | IDO1 (0.45) | IDO1TDO2SMN1; SMN2L3MBTL1SLC6A2 | |
| SCHEMBL5104539 | 0.89 | ALOX5 (0.42) | IDO1TDO2CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL18361615 | 0.81 | CYP3A4 (0.46) | IDO1TDO2SMN1; SMN2SLC6A2SLC6A3 | |
| SCHEMBL5518330 | 0.79 | CFTR (0.36) | IDO1TDO2CYP2A6SLC6A2SLC6A3 | |
| SCHEMBL7320352 | 0.79 | NR3C1 (0.36) | IDO1TDO2SLC6A2SLC6A3ALOX5 | |
| SCHEMBL20448486 | 0.79 | HTR1A (0.44) | SLC6A2SLC6A3HPGDHTR1AALOX5 | |
| Diphenylmethanol SCHEMBL10868602 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1CA12CA1CA2 | |
| Diphenylmethanol SCHEMBL6434457 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1CA12CA1CA2 | |
| Diphenylmethanol SCHEMBL41571 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1CA12CA1CA2 | |
| Diphenylmethanol SCHEMBL11564700 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563786-B2 | Method for producing optically active alcohol | MITSUI CHEMICALS, INC. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-04-12 | — | — | US | disclosed |
| EP-2412694-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | Mitsui Chemicals, Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-7387751-B2 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2008-06-17 | — | — | US | disclosed |
| US-7387751-B2 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2008-06-17 | — | — | US | disclosed |
| US-7384580-B2 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2008-06-10 | — | — | US | disclosed |
| US-7384580-B2 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2008-06-10 | — | — | US | disclosed |
| CN-100334085-C | Quinuclidine compound and medicine containing the same as active ingredient | EISAI R & D CO LTD (JP) | 2007-08-29 | — | — | CN | disclosed |
| US-20070194468-A1 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070194468-A1 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2007-08-23 | — | — | US | disclosed |
| US-6599917-B1 | A squalene-synthesizing enzyme inhibitor, a cholesterol biosynthesis inhibitor and a triglyceride biosynthesis inhibitor | EISAI CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| CN-1377349-A | Quinuclidine compound and medicine containing the same as active ingredient | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1217001-A1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-5258360-A | Fungicides, insecticides or plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | disclosed |
| US-5160364-A | Thiophene substituted acrylic derivatives; insecticides, plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-11-03 | — | — | US | disclosed |
| US-5073184-A | Agricultural fungicides, insecticides, plant growth regulators | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-17 | — | — | US | disclosed |
| US-5053073-A | THIOPHENE DERIVATIVES USEFUL AS FUNGICIDAL, INSECTICIDAL OR PLANT GROWTH REGULATING AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0243014-B1 | FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-06 | — | — | EP | disclosed |
| US-4863503-A | THIOPHENE DERIVATIVES, INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-05 | — | — | US | disclosed |
| EP-0243014-A1 | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070194468-A1 | Method of preparing organomagnesium compounds | SCLY, LIG3, LIG4 | IDO1 220/4885TDO2 1539/4885SMN1; SMN2 4369/4885 |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | ADH1A, ADH1C, FHIT | IDO1 4327/4885TDO2 1885/4885SMN1; SMN2 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.