Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | PNMT | P11086 | 6/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | CDC25C | P30307 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9769478 | 0.88 | HTR2A (0.50) | SIGMAR1KCNH2CDC25C | |
| SCHEMBL9716410 | 0.87 | PNMT (0.48) | KCNH2PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL14878929 | 0.82 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL9769475 | 0.81 | KCNH2 (0.54) | KCNH2PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL30561524 | 0.80 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL1640125 | 0.80 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8176570 | 0.79 | GRIN2B (0.49) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL3085819 | 0.76 | SIGMAR1 (0.48) | SIGMAR1KCNH2CDC25C | |
| SCHEMBL9628028 | 0.75 | KCNH2 (0.74) | SIGMAR1KCNH2CDC25C | |
| SCHEMBL12004879 | 0.75 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006561-A | Indane sulfonamide anti-arrhythmic agents and use | PFIZER INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0286278-A1 | Indanamine derivatives useful as antiarrhythmic agents | Pfizer Limited (GB) | 1988-10-12 | — | — | EP | disclosed |