SCHEMBL9769697

SCHEMBL9769697

O=S(=O)(O)Nc1ccc(O)c2ccccc12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 2/20 0.71
KAT2B Q92831 2/20 0.71
KAT8 Q9H7Z6 2/20 0.71
IDO1 P14902 5/20 0.60
HKDC1 Q2TB90 3/20 0.59
MEN1 O00255 5/20 0.58
KMT2A Q03164 5/20 0.58
BRAF P15056 1/20 0.58
GAA P10253 4/20 0.55
ALDH1A1 P00352 2/20 0.55
TP53 P04637 2/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
ALOX15 P16050 2/20 0.55
CASP1 P29466 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
HSD17B10 Q99714 2/20 0.55
PSD A5PKW4 1/20 0.55
MITF O75030 1/20 0.55
LMNA P02545 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30669737 0.83 EP300 (1.00) EP300KAT2BKAT8IDO1HKDC1
SCHEMBL15894583 0.83 EP300 (1.00) EP300KAT2BKAT8IDO1HKDC1
Diphenylether SCHEMBL11369726 0.81 EP300 (0.49) EP300KAT2BKAT8HKDC1MEN1
SCHEMBL10408858 0.80 EP300 (0.70) EP300KAT2BKAT8IDO1HKDC1
SCHEMBL589708 0.80 HKDC1 (0.77) EP300KAT2BKAT8HKDC1MEN1
1-Naphthol SCHEMBL27455138 0.79 KEAP1 (0.57) EP300KAT2BKAT8MEN1KMT2A
SCHEMBL9488680 0.78 EP300 (0.61) EP300KAT2BKAT8IDO1HKDC1
SCHEMBL11640095 0.76 EP300 (0.59) EP300KAT2BKAT8IDO1HKDC1
SCHEMBL1075937 0.75 GAA (0.55) EP300KAT2BKAT8MEN1KMT2A
SCHEMBL10158309 0.75 IDO1 (1.00) EP300KAT2BKAT8IDO1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5039589-A Microencapsulation FUJI PHOTO FILM CO., LTD. (JP) 1991-08-13 US disclosed