SCHEMBL589708

SCHEMBL589708

O=S(=O)(Nc1ccc(O)c2ccccc12)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 3/20 0.77
EP300 Q09472 2/20 0.77
KAT2B Q92831 2/20 0.77
KAT8 Q9H7Z6 2/20 0.77
GAA P10253 4/20 0.71
KMT2A Q03164 3/20 0.71
ALDH1A1 P00352 2/20 0.71
GFER P55789 2/20 0.71
MEN1 O00255 2/20 0.71
PSD A5PKW4 1/20 0.71
MITF O75030 1/20 0.71
LMNA P02545 1/20 0.71
TP53 P04637 1/20 0.71
MAPT P10636 1/20 0.71
THRB P10828 1/20 0.71
HPGD P15428 1/20 0.71
ALOX15 P16050 1/20 0.71
CASP1 P29466 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
HSD17B10 Q99714 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10409886 0.92 RECQL (0.68) HKDC1EP300KAT2BKAT8GAA
SCHEMBL808104 0.87 EP300 (1.00) HKDC1EP300KAT2BKAT8GAA
SCHEMBL17298738 0.84 PSD (1.00) HKDC1EP300KAT2BKAT8GAA
SCHEMBL21511039 0.84 GAA (1.00) HKDC1EP300KAT2BKAT8GAA
SCHEMBL16863960 0.83 MEN1 (0.75) HKDC1EP300KAT2BKAT8GAA
SCHEMBL14478903 0.82 EP300 (0.71) HKDC1EP300KAT2BKAT8GAA
SCHEMBL3260612 0.82 HKDC1 (0.66) HKDC1EP300KAT2BKAT8GAA
SCHEMBL9769697 0.80 EP300 (0.71) HKDC1EP300KAT2BKAT8GAA
SCHEMBL11636405 0.79 DDX3X (0.73) HKDC1EP300KAT2BKAT8GAA
SCHEMBL15894583 0.79 EP300 (1.00) HKDC1EP300KAT2BKAT8GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US claimed
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US disclosed
US-20230338340-A1 Methods of Treating Cystic Fibrosis DARTMOUTH COLLEGE (US) 2023-10-26 US disclosed
US-20230338340-A1 Methods of Treating Cystic Fibrosis DARTMOUTH COLLEGE (US) 2023-10-26 US disclosed
US-20230338340-A1 Methods of Treating Cystic Fibrosis DARTMOUTH COLLEGE (US) 2023-10-26 US disclosed
EP-4208021-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS Bio-Rad Laboratories, Inc. (US) 2023-07-12 EP disclosed
CN-116097093-A Preparation of Nucleated RBC (NRBC) analogs for use as reference blood controls in automated blood analyzers 生物辐射实验室股份有限公司 2023-05-09 CN disclosed
WO-2022094079-A1 METHODS OF TREATING CYSTIC FIBROSIS THE TRUSTEES OF DARTMOUTH COLLEGE (US) 2022-05-05 WO disclosed
WO-2022051443-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS BIO-RAD LABORATORIES, INC. (US) 2022-03-10 WO disclosed
US-20220065878-A1 PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS BIO-RAD LABORATORIES, INC. 2022-03-03 US disclosed
US-6265146-B1 SUPPORT HAVING THEREON AN ORGANIC SILVER SALT, A BINDER, A PHOTOSENSITIVE SILVER HALIDE, AN INFRARED-SENSITIZING DYE AND A HETEROATOM CONTAINING MACROCYCLIC COMPOUND. KONICA CORPORATION (JP) 2001-07-24 US disclosed
EP-1058151-A1 Silver halide photothermographic material KONICA CORPORATION (JP) 2000-12-06 EP disclosed
EP-1037102-A1 Image forming method of photothermographic material KONICA CORPORATION (JP) 2000-09-20 EP disclosed
EP-1033618-A1 Thermally developable photosensitive material KONICA CORPORATION (JP) 2000-09-06 EP disclosed
US-4546075-A TETRAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, OR BENZIMIDAZOLE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1985-10-08 US disclosed
US-4504568-A Sensitive silver halide photothermographic materials for producing dye images EASTMAN KODAK COMPANY (US) 1985-03-12 US disclosed
US-4452885-A USING THRIHALOMETHYL-3,4-OXADIAZOLES AS ANTIFOGGING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-06-05 US disclosed
US-4281060-A STABLE PHOTOGRAPHIC FILMS HAVING A COATING CONTAINING A POLYISOCYANATE OR A POLYISOCYANATE CONTAINING CARBAMATE GROUPS; WEAR RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1981-07-28 US disclosed
US-4104064-A Photoelectrophoretic imaging method employing dinaphtho-furan-dione pigments XEROX CORPORATION (US) 1978-08-01 US disclosed
US-3957829-A Certain dinaphtho[1,2-b;2',3'-d]-furan-7,12-diones XEROX CORPORATION (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338340-A1 Methods of Treating Cystic Fibrosis CFTR, DAB2IP, CTTN HKDC1 2753/4885EP300 2401/4885KAT2B 3962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.