SCHEMBL9770331

SCHEMBL9770331

COc1ccc(OCC(O)CSc2cccc(O)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.52
ADRB3 P13945 4/20 0.50
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
KDM4E B2RXH2 2/20 0.43
PPARD Q03181 1/20 0.43
KMT2A Q03164 3/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
POLB P06746 2/20 0.42
ADRB2 P07550 1/20 0.42
ADRB1 P08588 1/20 0.42
MTNR1A P48039 3/20 0.41
MTNR1B P49286 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9770474 0.91 BACE1 (0.62) BACE1ADRB3KDM4EPPARDKMT2A
SCHEMBL9770507 0.90 BACE1 (0.52) BACE1ADRB3TSHRMAPK1KDM4E
SCHEMBL9770448 0.88 BACE1 (0.59) BACE1ADRB3TSHRKDM4EPPARD
SCHEMBL9770497 0.87 NPC1 (0.57) BACE1MAPK1PPARDKMT2ANPC1
SCHEMBL9770535 0.86 BACE1 (0.57) BACE1MAPK1PPARDKMT2ANPC1
SCHEMBL9770472 0.85 MAPT (0.58) BACE1PPARDPOLBALDH1A1
SCHEMBL9770149 0.83 BACE1 (0.67) BACE1ADRB3MAPK1KDM4EKMT2A
SCHEMBL9770581 0.82 ALDH1A1 (0.48) BACE1TSHRMAPK1KMT2APOLB
SCHEMBL9770370 0.82 BACE1 (0.53) BACE1MAPK1PPARDKMT2ASMN1; SMN2
SCHEMBL9770514 0.81 CA1 (0.45) BACE1ADRB3TSHRMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5071822-A Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability KAO CORPORATION (JP) 1991-12-10 US disclosed